What Are these?
Exosomes are messenger particles that release naturally from a cell. These particles are responsible for cell-to-cell communication. Exosomes carry information and proteins to cells throughout your body, creating paths for communication between cells. These messenger cells can release growth factors and help other beneficial processes.
Also known as extracellular vesicles (particles that release naturally from a cell that cannot replicate), they are responsible for cell-to-cell communication. When used in exosome treatment, these biomolecules can be specifically targeted to stimulate a desired response in the body. This innovative treatment has shown great promise in various medical applications, including cancer treatment, tissue repair, and immune modulation.
Clinical Applications?
The main clinical application of exosomes are using them as a biomarker, cell-free therapeutic agents, drug delivery carriers, basic analysis for exosome kinetics, and cancer vaccine. Different exosomes from human or plant sources are utilized in various clinical trials.
Exosome therapies are currently being used for Cosmetic facial rejuvenation, hair growth, anti-aging and general well-being in clinics around the United States. But there is minimal data proving safety and efficacy. These studies (outlined below) argue that exosomes may have therapeutic abilities, but researchers have found no conclusive evidence.
If you are considering exosome treatment for a medical condition, it is important to research and consult a qualified healthcare professional. Exosomes are experimental treatments and are currently NOT approved by the Food and Drug Administration (FDA) to treat or diagnose any disease.
Regenerative medicine is being used in clinics in United States for arthritis, sports injuries, cancer, chronic pain and auto-immune conditions. The cell and cell free regenerative treatments are derived from Autologous ( patient's own) and Allogeneic source which include neonatal tissue such as placenta, cord and amniotic fluid. Tremendous amount of research is currently ongoing around the world sourcing these products to find treatments for various conditions and even aging.
These treatments may also hold the key to unlocking your desired sexual and physical enhancement. With Autologous (your own) regenerative therapies, physicians can harness the power of natural growth factors, cytokines, extracellular vesicles (exosomes) and other regenerative molecules present in your own body tissues such as blood, fat and bone marrow.
This can help boost cellular regeneration and tissue rejuvenation kickstarting the body's own healing processes, helping enhance penile size, erection and pleasure while optimizing the health of penile tissue, nerves, and blood vessels.
Many studies around the world show the rejuvenating benefits of Stem Cell and Exosome Therapy to decrease inflammation
and support tissue & cell regeneration.
Cell-Free Therapy
Exosome therapy is a cell-free regenerative treatment which rapidly stimulates the body’s natural healing mechanism, promoting faster healing and recovery and local tissue repair.
Exosome therapy is gaining in popularity within the United States. Few clinics are hailing exosome therapy as new miracle cure for anti-aging, immune function, chronic pain and autoimmune conditions. Some of these entities state that exosomes are more potent than stem cells at combating certain conditions. But there is minimal data proving safety and efficacy. These studies (outlined below) argue that exosomes may have therapeutic abilities, but researchers have found no conclusive evidence.
Exosomes therapies have been reported to help:
o reduces inflammation throughout the body to help heal cellular damage caused
by age, illness, and disease
o your body reduce inflammation and repair damaged tissue and cells, promoting
healthy cell regeneration
o Provides your cells the resources they need to help keep your immune system
strong and improve recovery time
o Supports healthy metabolic function to help you lose weight, build healthy
muscle tone, and increase energy levels
o Supports a healthy brain as well as reverses neurological damage for improved
cognitive function and mental clarity
The intrinsic, biological properties of neonatal and adult MSC exosomes demonstrated in laboratory and clinical studies indicate their potential as investigational biologic agents for the
treatment of injury and disease.
Different exosomes from human or plant sources are being utilized currently in various clinical trials. Most researchers use exosomes from the mesenchymal stem cells and neonatal tissues for biomarker and clinical use experiments.
As we age, our regenerative abilities decline as these cells cease to communicate or work in balance, resulting in chronic inflammation and pain. Exosome therapy enhances communication between these cells to properly regulate the body's healing response and support T-cells and NK cells to work in balance.
By: AndroMagnus Team
References
Edgar, James R. “Q&A: What Are Exosomes, Exactly?” BMC Biology, BioMed Central, 13 June 2016 https://bmcbiol.biomedcentral.com/articles/10.1186/s12915-016-0268-z.
Yu, Bo, et al. “Exosomes Derived from Mesenchymal Stem Cells.” International Journal of Molecular Sciences, vol. 15, no. 3, July 2014, pp. 4142–4157., doi:10.3390/ijms15034142.
Zhang, Y., Liu, Y., Liu, H., & Tang, W. H. (2019, February 15). Exosomes: Biogenesis, biologic function and clinical potential - cell & bioscience. BioMed Central. Retrieved February 3, 2022, from https://cellandbioscience.biomedcentral.com/articles/10.1186/s13578-019-0282-2
Pegtel DM, Gould SJ. Exosomes. Annu Rev Biochem. 2019 Jun 20;88:487-514. doi: 10.1146/annurev-biochem-013118-111902. PMID: 31220978.
A. Wei F. Chen, H. Zhang S. He, 276 Adipose-derived stem cell-derived exosomes ameliorate erectile dysfunction in a rat model of type 2 diabetes, The Journal of Sexual Medicine, July 2018 Volume 15, Issue 7, Supplement 3, Page S234
Ouyang X, Han X, Chen Z, Fang J, Huang X, Wei Hm MSC-derived exosomes ameliorate erectile dysfunction by alleviation of corpus cavernosum smooth muscle apoptosis in a rat model of cavernous nerve injury. Stem Cell Res Ther. 2018 Sep 26;9(1):246. doi: 10.1186/s13287-018-1003-1
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